Breast Tenderness

    Last Updated: April 29, 2017

    Breast tenderness refers to the actual physical tenderness of breast tissue, usually associated with a small amount of pain. Breast tenderness tends to be a symptom of PMS or menopause, and supplements that reduce those symptoms help with breast tenderness.

    examine-databaseExamine Database

    Examine Database: Breast Tenderness

    What works and what doesn't?

    Unlock the full potential of Examine

    Get started

    Examine Database References

    1. Pyridoxine (Vitamin B6) - Shobeiri F, Oshvandi K, Nazari MClinical effectiveness of vitamin E and vitamin B6 for improving pain severity in cyclic mastalgiaIran J Nurs Midwifery Res.(2015 Nov-Dec)
    2. Chaste tree - Ma L, Lin S, Chen R, Zhang Y, Chen F, Wang XEvaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese womenAust N Z J Obstet Gynaecol.(2010 Apr)
    3. Chaste tree - Schellenberg R, Zimmermann C, Drewe J, Hoexter G, Zahner CDose-dependent efficacy of the Vitex agnus castus extract Ze 440 in patients suffering from premenstrual syndromePhytomedicine.(2012 Sep 27)
    4. Vitamin E - Parsay S, Olfati F, Nahidi STherapeutic effects of vitamin E on cyclic mastalgiaBreast J.(2009 Sep-Oct)
    5. Chaste tree - Mirghafourvand M, Mohammad-Alizadeh-Charandabi S, Ahmadpour P, Javadzadeh YEffects of Vitex agnus and Flaxseed on cyclic mastalgia: A randomized controlled trialComplement Ther Med.(2016 Feb)
    6. Krill Oil - Sampalis F, Bunea R, Pelland MF, Kowalski O, Duguet N, Dupuis SEvaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrheaAltern Med Rev.(2003 May)
    7. Chaste tree - Momoeda M, Sasaki H, Tagashira E, Ogishima M, Takano Y, Ochiai KEfficacy and safety of Vitex agnus-castus extract for treatment of premenstrual syndrome in Japanese patients: a prospective, open-label studyAdv Ther.(2014 Mar)
    8. Chaste tree - Zamani M, Neghab N, Torabian STherapeutic effect of Vitex agnus castus in patients with premenstrual syndromeActa Med Iran.(2012)
    9. Serrapeptase - Kee WH, Tan SL, Lee V, Salmon YMThe treatment of breast engorgement with Serrapeptase (Danzen): a randomised double-blind controlled trialSingapore Med J.(1989 Feb)
    10. Fish Oil - Sohrabi N, Kashanian M, Ghafoori SS, Malakouti SKEvaluation of the effect of omega-3 fatty acids in the treatment of premenstrual syndrome: "a pilot trial"Complement Ther Med.(2013 Jun)
    11. Evening Primrose Oil - Ahmad Adni LL, Norhayati MN, Mohd Rosli RR, Muhammad JA Systematic Review and Meta-Analysis of the Efficacy of Evening Primrose Oil for Mastalgia Treatment.Int J Environ Res Public Health.(2021-Jun-10)