Examine Database: Sleep Quality
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Melatonin may reduce the frequency and duration of migraine attacks
In this randomized controlled trial, taking a melatonin supplement nightly reduced the frequency and duration of migraine attacks in adults with episodic migraine.
Mindfulness-based stress reduction interventions for sleep and fatigue in nurses
Prebiotic fiber for cognitive function, mood, and sleep
Lemon verbena for improving sleep
Cognitive behavioral therapy for insomnia among people with diabetes
Examine Database References
- Ginkgo Biloba - Hemmeter U, Annen B, Bischof R, Brüderlin U, Hatzinger M, Rose U, Holsboer-Trachsler EPolysomnographic effects of adjuvant ginkgo biloba therapy in patients with major depression medicated with trimipraminePharmacopsychiatry.(2001 Mar)
- Cannabis - Elaine G Boland, Michael I Bennett, Victoria Allgar, Jason W BolandCannabinoids for adult cancer-related pain: systematic review and meta-analysisBMJ Support Palliat Care.(2020 Mar)
- Saffron - Graham Kell, Amanda Rao, Gavin Beccaria, Paul Clayton, Antonio Manuel Inarejos-García, Marin Prodanovaffron ® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trialComplement Ther Med.(2017 Aug)
- PQQ - Masahiko Nakano, Tetsuro Yamamoto, Hisayoshi Okamura, Akira Tsuda, Yasuyuki KowatariEffects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and SleepFunctional Foods in Health and Disease.()
- Glycine - Kentaro Inagawa, Takenori Hiraoka, Tohru Kohda, Wataru Yamadera, Michio TakahashiSubjective effects of glycine ingestion before bedtime on sleep qualitySleep and Biological Rhythms.()
- Kanna - Chiu S, Gericke N, Farina-Woodbury M, Badmaev V, Raheb H, Terpstra K, Antongiorgi J, Bureau Y, Cernovsky Z, Hou J, Sanchez V, Williams M, Copen J, Husni M, Goble LProof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer's DementiaEvid Based Complement Alternat Med.(2014)
- Ginkgo Biloba - Murray BJ, Cowen PJ, Sharpley ALThe effect of Li 1370, extract of Ginkgo biloba, on REM sleep in humansPharmacopsychiatry.(2001 Jul)
- Cannabis - Derick T Wade, Petra Makela, Philip Robson, Heather House, Cynthia BatemanDo cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patientsMult Scler.(2004 Aug)
- Saffron - Adrian L Lopresti, Stephen J Smith, Alexandra P Metse, Peter D DrummondEffects of saffron on sleep quality in healthy adults with self-reported poor sleep: a randomized, double-blind, placebo-controlled trialJ Clin Sleep Med.(2020 Jun 15)
- Saffron - Alireza Milajerdi, Shima Jazayeri, Elham Shirzadi, Najmeh Hashemzadeh, Atieh Azizgol, Abolghassem Djazayery, Ahmad Esmaillzadeh, Shahin AkhondzadehThe effects of alcoholic extract of saffron (Crocus satious L.) on mild to moderate comorbid depression-anxiety, sleep quality, and life satisfaction in type 2 diabetes mellitus: A double-blind, randomized and placebo-controlled clinical trialComplement Ther Med.(2018 Dec)
- Glycine - Wataru Yamadera, Kentaro Inagawa, Shintaro Chiba, Makoto Bannai, Michio Takahashi, Kazuhiko NakayamaGlycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changesSleep and Biological Rhythms.()
- Cannabis - M Serpell, S Ratcliffe, J Hovorka, M Schofield, L Taylor, H Lauder, E EhlerA double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatmentEur J Pain.(2014 Aug)
- Saffron - Shahdadi H, Balouchi A, Dehghanmehr S Effect of saffron oral capsule on anxiety and quality of sleep of diabetic patients in a tertiary healthcare facility in southeastern Iran: A quasi-experimental studyTrop J Pharm Res.()
- Lion's Mane - Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki KReduction of depression and anxiety by 4 weeks Hericium erinaceus intakeBiomed Res.(2010 Aug)
- Binaural Beats - D E Shumov, I A Yakovenko, N N Alipov, Z V Bakaeva, E B Yakunina, A N Minyuk, A V Vinokurov, V B Dorokhov[The effect of music containing binaural beats on daytime fall-asleep dynamics]Zh Nevrol Psikhiatr Im S S Korsakova.(2020)
- Lavender - Namni Goel, Hyungsoo Kim, Raymund P LaoAn olfactory stimulus modifies nighttime sleep in young men and womenChronobiol Int.(2005)
- Vitamin D - Majid MS, Ahmad HS, Bizhan H, Hosein HZM, Mohammad AThe effect of vitamin D supplement on the score and quality of sleep in 20-50 year-old people with sleep disorders compared with control groupNutr Neurosci.(2018 Sep)
- Lavender - Kasper S, Gastpar M, Müller WE, Volz HP, Möller HJ, Dienel A, Schläfke SSilexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, placebo controlled trialInt Clin Psychopharmacol.(2010 Sep)
- Rhodiola Rosea - Cropley M, Banks AP, Boyle JThe Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood SymptomsPhytother Res.(2015 Dec)
- Valerian - Leathwood PD, Chauffard FAqueous extract of valerian reduces latency to fall asleep in manPlanta Med.(1985 Apr)
- Melatonin - Luthringer R, Muzet M, Zisapel N, Staner LThe effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomniaInt Clin Psychopharmacol.(2009 Sep)
- Glycine - Bannai M, Kawai N, Ono K, Nakahara K, Murakami NThe effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteersFront Neurol.(2012 Apr 18)
- Lavender - Li-Wei Chien, Su Li Cheng, and Chi Feng LiuThe Effect of Lavender Aromatherapy on Autonomic Nervous System in Midlife Women with InsomniaEvidence-Based Complementary and Alternative Medicine.()
- 16:8 Intermittent Fasting - Grant M Tinsley, M Lane Moore, Austin J Graybeal, Antonio Paoli, Youngdeok Kim, Joaquin U Gonzales, John R Harry, Trisha A VanDusseldorp, Devin N Kennedy, Megan R CruzTime-restricted feeding plus resistance training in active females: a randomized trialAm J Clin Nutr.(2019 Sep 1)
- Cannabis - Turo J Nurmikko, Mick G Serpell, Barbara Hoggart, Peter J Toomey, Bart J Morlion, Derek HainesSativex successfully treats neuropathic pain characterised by allodynia: a randomised, double-blind, placebo-controlled clinical trialPain.(2007 Dec 15)
- Valerian - Fernández-San-Martín MI, Masa-Font R, Palacios-Soler L, Sancho-Gómez P, Calbó-Caldentey C, Flores-Mateo GEffectiveness of Valerian on insomnia: a meta-analysis of randomized placebo-controlled trialsSleep Med.(2010 Jun)
- Melatonin - Uchechukwu C Megwalu, Joshua E Finnell, Jay F PiccirilloThe effects of melatonin on tinnitus and sleepOtolaryngol Head Neck Surg.(2006 Feb)
- Theanine - Shinsuke Hidese, Miho Ota, Chisato Wakabayashi, Takamasa Noda, Hayato Ozawa, Tsutomu Okubo, Hiroshi KunugiEffects of chronic l-theanine administration in patients with major depressive disorder: an open-label studyActa Neuropsychiatr.(2017 Apr)
- DHEA - Dayal M, Sammel MD, Zhao J, Hummel AC, Vandenbourne K, Barnhart KTSupplementation with DHEA: effect on muscle size, strength, quality of life, and lipidsJ Womens Health (Larchmt).(2005 Jun)
- Lavender - George T Lewith, Anthony Dean Godfrey, Philip PrescottA single-blinded, randomized pilot study evaluating the aroma of Lavandula augustifolia as a treatment for mild insomniaJ Altern Complement Med.(2005 Aug)
- Melatonin - Lemoine P, Nir T, Laudon M, Zisapel NProlonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effectsJ Sleep Res.(2007 Dec)
- Panax Ginseng (Korean Ginseng) - Kitaoka K, Uchida K, Okamoto N, Chikahisa S, Miyazaki T, Takeda E, Séi HFermented ginseng improves the first-night effect in humansSleep.(2009 Mar)
- Fish Oil - Jahangard L, Sadeghi A, Ahmadpanah M, Holsboer-Trachsler E, Sadeghi Bahmani D, Haghighi M, Brand SInfluence of adjuvant omega-3-polyunsaturated fatty acids on depression, sleep, and emotion regulation among outpatients with major depressive disorders - Results from a double-blind, randomized and placebo-controlled clinical trialJ Psychiatr Res.(2018 Dec)
- Valerian - Barton DL, Atherton PJ, Bauer BA, Moore DF Jr, Mattar BI, Lavasseur BI, Rowland KM Jr, Zon RT, Lelindqwister NA, Nagargoje GG, Morgenthaler TI, Sloan JA, Loprinzi CLThe use of Valeriana officinalis (Valerian) in improving sleep in patients who are undergoing treatment for cancer: a phase III randomized, placebo-controlled, double-blind study (NCCTG Trial, N01C5)J Support Oncol.(2011 Jan-Feb)
- Fish Oil - Watanabe N, Matsuoka Y, Kumachi M, Hamazaki K, Horikoshi M, Furukawa TAOmega-3 fatty acids for a better mental state in working populations - Happy Nurse Project: A 52-week randomized controlled trialJ Psychiatr Res.(2018 Jul)
- Theanine - Lyon MR, Kapoor MP, Juneja LRThe effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trialAltern Med Rev.(2011 Dec)
- Quercetin - Bigelman KA, Chapman DP, Freese EC, Trilk JL, Cureton KJEffects of 6 weeks of quercetin supplementation on energy, fatigue, and sleep in ROTC cadetsMil Med.(2011 May)
- Chaste tree - Momoeda M, Sasaki H, Tagashira E, Ogishima M, Takano Y, Ochiai KEfficacy and safety of Vitex agnus-castus extract for treatment of premenstrual syndrome in Japanese patients: a prospective, open-label studyAdv Ther.(2014 Mar)
- Melatonin - André Schwertner, Claudia C Conceição Dos Santos, Gislene Dalferth Costa, Alícia Deitos, Andressa de Souza, Izabel Cristina Custodio de Souza, Iraci L S Torres, João Sabino L da Cunha Filho, Wolnei CaumoEfficacy of melatonin in the treatment of endometriosis: a phase II, randomized, double-blind, placebo-controlled trialPain.(2013 Jun)
- Lavender - Mahin Moeini, Maryam Khadibi, Reza Bekhradi, Seyed Ahmad Mahmoudian, Fatemeh NazariEffect of aromatherapy on the quality of sleep in ischemic heart disease patients hospitalized in intensive care units of heart hospitals of the Isfahan University of Medical SciencesIran J Nurs Midwifery Res.(Fall 2010)
- Magnesium - Held K, Antonijevic IA, Künzel H, Uhr M, Wetter TC, Golly IC, Steiger A, Murck HOral Mg(2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humansPharmacopsychiatry.(2002 Jul)
- Kava - Lehrl SClinical efficacy of kava extract WS 1490 in sleep disturbances associated with anxiety disorders. Results of a multicenter, randomized, placebo-controlled, double-blind clinical trialJ Affect Disord.(2004 Feb)
- 16:8 Intermittent Fasting - Kelsey Gabel, Kristin K Hoddy, Helen J Burgess, Krista A VaradyEffect of 8-h time-restricted feeding on sleep quality and duration in adults with obesityAppl Physiol Nutr Metab.(2019 Aug)
- Kava - D WheatleyKava and valerian in the treatment of stress-induced insomniaPhytother Res.(2001 Sep)
- Valerian - Mirabi P, Mojab FThe effects of valerian root on hot flashes in menopausal womenIran J Pharm Res.(2013 Winter)
- Lavender - Inn-Sook Lee, Gyung-Joo Lee[Effects of lavender aromatherapy on insomnia and depression in women college students]Taehan Kanho Hakhoe Chi.(2006 Feb)
- Fish Oil - Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, Carpenter JS, Learman LA, Newton KM, Reed SD, Manson JE, Sternfeld B, Caan B, Freeman EW, LaCroix AZ, Tinker LF, Booth-Laforce C, Larson JC, Anderson GLEfficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trialMenopause.(2014 Apr)
- Cannabis - Marie T Fallon, Eberhard Albert Lux, Robert McQuade, Sandro Rossetti, Raymond Sanchez, Wei Sun, Stephen Wright, Aron H Lichtman, Elena KornyeyevaSativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studiesBr J Pain.(2017 Aug)
- Creatine - Avi Leader, Daniella Amital, Alan Rubinow, Howard AmitalAn open-label study adding creatine monohydrate to ongoing medical regimens in patients with the fibromyalgia syndromeAnn N Y Acad Sci.(2009 Sep)
- Cannabis - Russell K Portenoy, Elena Doina Ganae-Motan, Silvia Allende, Ronald Yanagihara, Lauren Shaiova, Sharon Weinstein, Robert McQuade, Stephen Wright, Marie T FallonNabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trialJ Pain.(2012 May)
- Valerian - Taibi DM, Bourguignon C, Gill Taylor AA feasibility study of valerian extract for sleep disturbance in person with arthritisBiol Res Nurs.(2009 Apr)
- Cannabis - David J Rog, Turo J Nurmikko, Tim Friede, Carolyn A YoungRandomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosisNeurology.(2005 Sep 27)
- Spirulina - Sajjad Moradi, Mehdi Zobeiri, Awat Feizi, Cain C T Clark, Mohammad Hassan EntezariThe effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative colitis: A randomised, double-blinded, placebo-controlled trialInt J Clin Pract.(2021 Jun 9)
- Cannabis - Mark A Ware, Tongtong Wang, Stan Shapiro, Ann Robinson, Thierry Ducruet, Thao Huynh, Ann Gamsa, Gary J Bennett, Jean-Paul ColletSmoked cannabis for chronic neuropathic pain: a randomized controlled trialCMAJ.(2010 Oct 5)
- Red Clover Extract - Lipovac M, Chedraui P, Gruenhut C, Gocan A, Kurz C, Neuber B, Imhof MEffect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal WomenObstet Gynecol Int.(2011)
- Binaural Beats - Vera Abeln, Jens Kleinert, Heiko K Strüder, Stefan SchneiderBrainwave entrainment for better sleep and post-sleep state of young elite soccer players - a pilot studyEur J Sport Sci.(2014)
- Cannabis - Zajicek J, Fox P, Sanders H, Wright D, Vickery J, Nunn A, Thompson A, UK MS Research GroupCannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trialLancet.(2003 Nov 8)
- Cannabis - Letizia Leocani, Arturo Nuara, Elise Houdayer, Irene Schiavetti, Ubaldo Del Carro, Stefano Amadio, Laura Straffi, Paolo Rossi, Vittorio Martinelli, Carlos Vila, Maria Pia Sormani, Giancarlo ComiSativex(®) and clinical-neurophysiological measures of spasticity in progressive multiple sclerosisJ Neurol.(2015 Nov)
- Magnesium - Nielsen FH, Johnson LK, Zeng HMagnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleepMagnes Res.(2010 Dec)
- Lavender - B Uehleke, S Schaper, A Dienel, S Schlaefke, R StangePhase II trial on the effects of Silexan in patients with neurasthenia, post-traumatic stress disorder or somatization disorderPhytomedicine.(2012 Jun 15)
- Saffron - Amir Ghaderi, Omid Asbaghi, Željko Reiner, Fariba Kolahdooz, Elaheh Amirani, Hamed Mirzaei, Hamid Reza Banafshe, Parisa Maleki Dana, Zatollah AsemiThe effects of saffron (Crocus sativus L.) on mental health parameters and C-reactive protein: A meta-analysis of randomized clinical trialsComplement Ther Med.(2020 Jan)
- Echinacea - Tiralongo E, Lea RA, Wee SS, Hanna MM, Griffiths LRRandomised, double blind, placebo-controlled trial of echinacea supplementation in air travellersEvid Based Complement Alternat Med.(2012)
- Melatonin - Hurtuk A, Dome C, Holloman CH, Wolfe K, Welling DB, Dodson EE, Jacob AMelatonin: can it stop the ringing?Ann Otol Rhinol Laryngol.(2011-Jul)
- Ashwagandha - Langade D, Kanchi S, Salve J, Debnath K, Ambegaokar DEfficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled StudyCureus.(2019 Sep 28)
- Theanine - Shinsuke Hidese, Shintaro Ogawa, Miho Ota, Ikki Ishida, Zenta Yasukawa, Makoto Ozeki, Hiroshi KunugiEffects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled TrialNutrients.(2019 Oct 3)
- Ornithine - Kokubo T, Ikeshima E, Kirisako T, Miura Y, Horiuchi M, Tsuda AA randomized, double-masked, placebo-controlled crossover trial on the effects of L-ornithine on salivary cortisol and feelings of fatigue of flushers the morning after alcohol consumptionBiopsychosoc Med.(2013 Feb 18)
- Coenzyme Q10 - Mario D Cordero, Elísabet Alcocer-Gómez, Manuel de Miguel, Ognjen Culic, Angel M Carrión, José Miguel Alvarez-Suarez, Pedro Bullón, Maurizio Battino, Ana Fernández-Rodríguez, José Antonio Sánchez-AlcazarCan coenzyme q10 improve clinical and molecular parameters in fibromyalgia?Antioxid Redox Signal.(2013 Oct 20)
- Ashwagandha - Salve J, Pate S, Debnath K, Langade DAdaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical StudyCureus.(2019 Dec 25)
- Tart Cherry Juice - Glyn Howatson, Phillip G Bell, Jamie Tallent, Benita Middleton, Malachy P McHugh, Jason EllisEffect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep qualityEur J Nutr.(2012 Dec)
- Tart Cherry Juice - Hillman AR, Trickett O, Brodsky C, Chrismas BMontmorency tart cherry supplementation does not impact sleep, body composition, cellular health, or blood pressure in healthy adults.Nutr Health.(2022-Jul-05)
- Tart Cherry Juice - Kimble R, Keane KM, Lodge JK, Cheung W, Haskell-Ramsay CF, Howatson GPolyphenol-rich tart cherries ( Montmorency) improve sustained attention, feelings of alertness and mental fatigue and influence the plasma metabolome in middle-aged adults: a randomised, placebo-controlled trial.Br J Nutr.(2022-Feb-03)
- Tart Cherry Juice - Chung J, Choi M, Lee KEffects of Short-Term Intake of Montmorency Tart Cherry Juice on Sleep Quality after Intermittent Exercise in Elite Female Field Hockey Players: A Randomized Controlled Trial.Int J Environ Res Public Health.(2022-Aug-18)
- Magnesium - Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann DMagnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study.Sleep.(1998-Aug-01)
- Magnesium - Mohammad Alizadeh, Majid Karandish, Mohammad Asghari Jafarabadi, Lida Heidari, Roshan Nikbakht, Hossein Babaahmadi Rezaei, Reihaneh MousaviMetabolic and hormonal effects of melatonin and/or magnesium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trialNutr Metab (Lond).(2021 Jun 6)
- Magnesium - Macian N, Dualé C, Voute M, Leray V, Courrent M, Bodé P, Giron F, Sonneville S, Bernard L, Joanny F, Menard K, Ducheix G, Pereira B, Pickering GShort-Term Magnesium Therapy Alleviates Moderate Stress in Patients with Fibromyalgia: A Randomized Double-Blind Clinical Trial.Nutrients.(2022-May-17)
- Magnesium - Saba S, Faizi F, Sepandi M, Nehrir BEffect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.Magnes Res.(2022-Apr-01)
- Nicotinamide Mononucleotide - Irie J, Inagaki E, Fujita M, Nakaya H, Mitsuishi M, Yamaguchi S, Yamashita K, Shigaki S, Ono T, Yukioka H, Okano H, Nabeshima YI, Imai SI, Yasui M, Tsubota K, Itoh HEffect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men.Endocr J.(2020-Feb-28)
- Valerian - Bent S, Padula A, Moore D, Patterson M, Mehling WValerian for sleep: a systematic review and meta-analysis.Am J Med.(2006-Dec)
- Valerian - Shinjyo N, Waddell G, Green JValerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis.J Evid Based Integr Med.(2020)
- Passionflower - Ngan A, Conduit RA double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality.Phytother Res.(2011-Aug)
- Iron - Tomer Avni, Shelley Reich, Nirit Lev, Anat Gafter-GviliIron supplementation for restless legs syndrome - A systematic review and meta-analysisEur J Intern Med.(2019 May)
- Saffron - Jinrong Lian, Yi Zhong, Hang Li, Siyuan Yang, Jiahe Wang, Xiang Li, Xinmin Zhou, Gang ChenEffects of saffron supplementation on improving sleep quality: a meta-analysis of randomized controlled trialsSleep Med.(2022 Apr)